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“If you have Hyperthyroidism/Graves’ disease or Hashimoto’s thyroiditis and are looking to reduce your toxic load while supporting your immune system, then consider taking Hepatommune.” – Dr. Eric Osansky

• Purity: Minimal fillers or unnecessary ingredients
• Rare combination of NAC, milk thistle, and schisandra to support the liver
• Cordyceps has both immune modulating and adaptogenic properties
• Other mushrooms have been shown to help with the Treg/Th17 balance, which is essential to supporting the autoimmune component of Graves’ disease and Hashimoto’s

Reduce your toxic load while at the same time supporting your immune system health.

Hepatommune is a synergistic formula designed to support healthy liver and immune function. It does not contain gluten, dairy, soy or GMOs

N-Acetyl-L-Cysteine (NAC).  NAC is an acetylated form of the amino acid cysteine, and it is a precursor to glutathione, which is an antioxidant that plays an important role in supporting the detoxification pathways.  In addition to increasing glutathione levels, NAC can also act as a gentle heavy metal chelator, and it can also play a role in supporting the inflammatory response and calming oxidative stress, which is a factor with all autoimmune conditions, including Graves’ disease and Hashimoto’s thyroiditis.

Reishi Full Spectrum.  A few different studies show that Ganoderma lucidium has hepatoprotective (liver protecting) effects (1) (2).  It has also been widely used for the prevention and treatment of gastric cancer (3), hypertension (4), arthritis (5), hepatoxicity (6), diabetes (7), asthma (8), nephrosis (9), and immunological disorders (10).  

As for how reishi can benefit people with Graves’ disease and Hashimoto’s, autoimmunity is characterized by an imbalance of regulatory T cells (Tregs) and Th17 cells. In order to suppress autoimmunity you want to have an abundance of Tregs and a lower amount of Th17 cells.  And numerous studies show that Reishi can help with this Th17/Treg balance (11) (12).

Cordyceps sinensis.  Research has shown that its properties include antiaging, reparative, anti-cancer, anti-inflammatory, and as an antioxidant (13).  As for its effects on the immune system, one study showed that C. sinensis reduced IL-17 by decreasing Th17 cells (14), which play a role in autoimmunity.  

A study involving 44 patients with Graves’ disease and 56 patients with Hashimoto’s thyroiditis showed that at the end of treatment TPO antibodies and TSH receptor antibodies decreased by 40.06% and 46.94% of baseline in the Graves’ disease patients (15).  TPO antibodies and anti-thyroglobulin antibodies decreased by 51.30% and 39.49% of baseline in the Hashimoto’s patients.

Milk Thistle.  This is one of the more popular herbs, as it is well known for its role in liver health. The active complex of milk thistle is composed of three isomer flavonolignans (silybin, silydianin, and silychristin) collectively known as silymarin.  Milk thistle has antioxidant activity and inhibits the binding of environmental toxins, and it can prevent or reduce the severity of liver damage (16).  This herb can help support the liver for those taking anti-thyroid medication.

Chinese Skullcap.  This is a common and widely used Chinese medicinal herb, and the main active compounds are baicalin and baicalein. They may act as antipyretic, analgesic, anti-inflammatory, antiallergenic, antimicrobial, and antitumor agents (17).

Schisandra Extract.  Schisandra (Schisandra chinensis) has been used for centuries as a plant of traditional Chinese medicine, and the lignans of schisandra has been investigated in hundreds of studies that have confirmed adaptogenic effects, central nervous system stimulation, hepatoprotective effects and potential anticancer potential (18).

Burdock Extract.  Burdock has been used therapeutically in Europe, North America and Asia for hundreds of years.  In the root, the active ingredients have been found to “detoxify” blood and promote blood circulation, and antioxidants and antidiabetic compounds have also been found (19).  In the seeds, some of the compounds possess anti-inflammatory effects (19).  Another study showed that burdock root tea significantly decreased the levels of hs-CRP, which is an inflammatory marker (20).

References:

https://pubmed.ncbi.nlm.nih.gov/27910775/ (1)

https://pubmed.ncbi.nlm.nih.gov/23796220/ (2)

https://pubmed.ncbi.nlm.nih.gov/12436306/ (3)

https://pubmed.ncbi.nlm.nih.gov/21801467/ (4)

https://pubmed.ncbi.nlm.nih.gov/17907228/ (5)

https://pubmed.ncbi.nlm.nih.gov/22659462/ (6)

https://pubmed.ncbi.nlm.nih.gov/25790910/ (7)

https://pubmed.ncbi.nlm.nih.gov/24948193/ (8)

https://pubmed.ncbi.nlm.nih.gov/15567896/ (9)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960732/ (10)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985119/ (11)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707273/ (12)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104941/ (13)

https://pubmed.ncbi.nlm.nih.gov/22001898/ (14)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045992/ (15)

https://pubmed.ncbi.nlm.nih.gov/20564545/ (16)

https://pubmed.ncbi.nlm.nih.gov/33917159/ (17)

https://pubmed.ncbi.nlm.nih.gov/31431019/ (18)

https://pubmed.ncbi.nlm.nih.gov/20981575/ (19)

https://pubmed.ncbi.nlm.nih.gov/25350500/ (20)

 

Serving Size: 4 Capsules
Servings Per Container: 30

• N-Acetyl-L-Cysteine 600mg *
• Reishi Full Spectrum 500mg *
  (Ganoderma spp.) (mycelium, fruiting body, primordia, and extracellular compounds)
• Cordyceps 500mg *
  (Cordyceps sinensis)(Mycelium)
  [Standardized to contain 8% cordycepic acid and 0.28% adenosine]
• Milk Thistle (Silybum marianum) (Seed) 500mg *
  [Standardized to contain 80% Silymarin]
• Chinese Skullcap Extract (Scutellaria baicalensis) (Root) 300mg *
  [Standardized to contain 30% flavones]
• Schisandra Extract (Schisandra chinensis) (Fruit) 250mg *
• Burdock Extract (Arctium lappa) (Root) 250mg *

*Daily Value not established.

Other Ingredients: Cellulose (capsule)‚ vegetable stearate‚ silicon dioxide.

Does not contain gluten, dairy, soy or GMOs.

STORE AT ROOM TEMPERATURE.

KEEP OUT OF REACH OF CHILDREN.

WARNING: This product contains a substance known to the State of California to cause birth defects or other reproductive harm.

www.P65Warnings.ca.gov/food