Episode - Can Berberine Increase the Effectiveness of Methimazole?


Can Berberine Increase the Effectiveness of Methimazole?

A recent study has shown that methimazole supplemented with berberine can improve therapeutic effects for people with Graves’ disease.

Does that mean those with Graves’ disease could benefit from berberine on its own as an agent that improves the gut microbiome? Based on this study, the answer seems to be yes.

Today I’m diving into this journal article, sharing the details of the study itself and my key takeaways for those with Graves’ disease.


During this episode, you’ll learn:

  • How this study was designed
  • Which markers were being measured in the study
  • The difference observed between the use of berberine with methimazole versus methimazole alone
  • Benefits of berberine for gut health
  • Evidence that intestinal microbes can contribute to the development of thyroid disease
  • The possible connection between Graves’ disease and Prevotella spp.


As always, I hope you found this episode valuable, and I look forward to catching you in the next episode!


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